Nowadays when you go in for a minor or major operation, there is no question over anaesthetic being used. That wasn't the case for patients until the 1840s, poor devils. Up until then the patient was, in some cases, restrained to stop them thrashing around and putting the surgeon off his work. If lucky the patient was given alcohol or opium to help ease the pain. In other cases a piece of wood or leather was given to bite down on or, if you were a soldier, a bullet. Illustration of a patient ready for surgery in the 16th century Taken from The History of Ophthalmology On 16th October 1846 John Collins Warren undertook the first surgical operation using ether as an anaesthetic in Massachusetts General Hospital in Boston. Less than three months later an Irish surgeon would carry out the first amputation under the influence of ether ever preformed in Ireland. John McDonnell, father of Robert McDonnell who has featured previously in this blog , was born in Belfast o...